By Kathleen Berger, Executive Producer for Science and Technology, in collaboration with University of Missouri Health Care
Teresa Woody has an impressive portfolio of stained-glass art.
“It was something that got my mind off of the life changes I was going through,” said Woody.
In 2005, those life changes centered around a medical diagnosis of obstructive sleep apnea, which disturbed her sleep up to 64 times per hour and wreaked havoc on her professional and personal life.
Obstructive sleep apnea is a common condition, affecting up to 30 million people in the U.S., in which the airway narrows or closes during sleep, causing breathing interruptions. Sleep apnea causes loud snoring, but it can also lead to more serious symptoms like extreme fatigue, high-blood pressure, heart problems and stroke.
Woody was prescribed a CPAP machine, which keeps the airway open by pushing pressurized air through a mask. Unfortunately for Woody, she also had a disease called pulmonary sarcoidosis that weakened her lungs. Over time, her lungs couldn’t handle the pressurized air from the CPAP, so she put the machine away and resigned herself to the idea she would just have to live with the limitations of untreated sleep apnea.
But in 2019, she regained some hope when she learned about a potential solution: an implantable device called Inspire.
“This hypoglossal nerve stimulation, or the Inspire device, has kind of revolutionized the way that we think about treating obstructive sleep apnea in a kind of a different modality,” said David Chang, MD, an ear, nose and throat surgeon at MU Health Care.
Dr. Chang implanted the pacemaker-sized device in Teresa’s during an outpatient procedure in 2020. The Inspire device is implanted just below the collar bone. It has a cabled sensor that is placed between the ribs next to the lung, and another cable connected to electrodes that are placed around a nerve to the tongue called the hypoglossal nerve. When a person takes a breath, the sensor around the lung detects this and sends that information to the generator. The device then sends a pulse to the electrodes around the hypoglossal nerve, which causes the tongue to push forward to keep the airway clear.
“A large part of sleep apnea is a lack of muscle tone in the throat and tongue region that causes that collapse to occur,” said Chang. “Inspire is a new way of treating that aspect of sleep apnea by adding that tone back to a sleeping person’s tongue to get it out of the way.”
After the standard one-month waiting period to allow her body to heal after surgery, Woody began using the device. Woody said after about a month of using the device and working with the Sleep Disorders Center to find the precise settings that worked best for her, she was finally able to sleep all the way through the night.
“When I woke up, I sat on my bed and I cried like a baby for 30 minutes,” she said. “I hadn’t had a good night’s sleep in 13 years at that point. It was life changing.”
At a follow-up sleep study three months after surgery, Woody had only two sleep disturbances in an hour, below the minimum of five per hour for a sleep apnea diagnosis. She no longer schedules her days around an afternoon nap and doesn’t limit herself to short drives at certain times of day. She now has the energy to keep up with her nine grandchildren and to make stained glass art.
“I had a 10-year break where I didn’t make a single solitary piece of stained glass,” she said. “I just didn’t have the energy, didn’t have the drive. After my Inspire, I started getting back into it, and now I’m teaching other people the thing that I love to do and giving away lots of gifts.”
The device is for adults who experience 15 to 65 sleep interruptions per hour, are not excessively overweight and can’t tolerate CPAP.