Key to Muscle Regeneration Discovered at Saint Louis University

    Saint Louis University researchers say the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries. They explain how REV-ERB helps coordinate our metabolism with our daily routine. They demonstrate that REV-ERB can stimulate muscle regeneration upon acute muscle injury in an animal model and suggest their findings reveal that REV-ERB may be a potent therapeutic target for the treatment of a myriad of muscle diseases, including muscular dystrophy, sarcopenia, and cachexia, in addition to acute injury.